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M94A0709.TXT
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1994-10-21
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Document 0709
DOCN M94A0709
TI Pneumonitis in association with primary HIV illness.
DT 9412
AU Kelly M; Lloyd A; Jones P; Department of Infectious Diseases, Prince
Henry Hospital, Little; Bay, Sydney.
SO Annu Conf Australas Soc HIV Med. 1993 Oct 28-30;5:26 (abstract no.
TC-1). Unique Identifier : AIDSLINE ASHM5/94348946
AB A 27 year old homosexual male presented initially with a 5 day illness
characterised by fever and rash. Apart from a maculopapular rash there
was no physical abnormality. The symptoms resolved spontaneously over a
four day period. At presentation P24Ag was positive and then became
negative whereas tests for HIV antibody were initially negative and then
became positive over a two week period. At presentation the CD4 count
was 180 x 10(6)/l and CD8 count was 340 x 10(6)/l. Four weeks after
discharge the patient represented with a 7 day febrile illness with
dyspnoea and cough. Fine crepitations were heard at the lung bases. The
PaO on room air was 73mmHg. The chest x-ray was normal. A bronchoscopy
was macroscopically normal. Immunofluorescent studies for Pneumocystis
carinii were negative. Bronchoalveolar lavage cell count revealed 60%
lymphocytes (73% CD8 and 18% CD4). The peripheral blood CD4 and CD8 cell
count were 250 x 10(6)/l and 1190 x 10(6)/l respectively. The patient
was commenced on steroids and supplemental oxygen and improved over a
three day period. Steroids were subsequently reduced and the patient
remained well. Pneumonitis is a rare but significant complication of
primary HIV illness which may respond to steroids.
DE Adrenal Cortex Hormones/THERAPEUTIC USE Adult Case Report Combined
Modality Therapy CD4-CD8 Ratio Diagnosis, Differential Homosexuality
Human HIV Seropositivity/*DIAGNOSIS/DRUG THERAPY/IMMUNOLOGY Leukocyte
Count Male Oxygen Inhalation Therapy Pneumonia/*DIAGNOSIS/DRUG
THERAPY/IMMUNOLOGY T4 Lymphocytes/IMMUNOLOGY MEETING ABSTRACT
SOURCE: National Library of Medicine. NOTICE: This material may be
protected by Copyright Law (Title 17, U.S.Code).